Leo Simpson, MD

Dr. Leo Simpson is an Assistant Professor at Baylor College of Medicine and is board-certified in Interventional Cardiology, Electrophysiology and Advanced Heart Failure and cardiac transplant. Show full bio

Dr. Simpson earned his medical degree and completed his residency at the All India Institute of Medical Sciences. His extensive training included residency in Internal Medicine at Emory University followed by Cardiology and Interventional Cardiology fellowship at St. Luke’s Episcopal Hospital/Texas Heart Institute and then Cardiac Electrophysiology at Baylor University Medical Center in Dallas. He is affiliated with Texas Heart Institute at Baylor St. Luke’s Medical Center and an active member of the Heart Failure and Cardiac Transplantation team at the Texas Heart Institute.

Dr. Simpson is a member of the American Society of Echocardiography and the American Society of Nuclear Cardiology and is a Fellow of the American College of Cardiology, Fellow of the Heart Rhythm Society and Fellow of Society for Cardiovascular Angiography and Intervention.

He is an expert in the field of percutaneously inserted biventricular mechanical circulatory support (Impella, Tandem and ECMO), both for the treatment of refractory shock, ARDS and to support high risk percutaneous coronary revascularization, as well as Electrophysiological procedures. He also specializes in Percutaneous Patent Foramen Ovale (PFO) closure, Percutaneous Atrial septal Defect (ASD) closure, and MitraClip – a less-invasive treatment option for certain people with mitral regurgitation who are not suitable for surgery.

In addition to his clinical pursuits, his primary research interest is in the field of treatment of advanced heart failure. Dr. Simpson currently runs as a sub-investigator a randomized trial study – INOVATE-HF (INcrease OF VAgal TonE in chronic heart failure, a randomized study to establish Safety and Efficacy of CardioFit for treatment of subjects with heart failure and Left Ventricular Dysfunction) in this field. He is also the co-author of multiple publications involving left ventricular assist device and cardiomyopathy.

Dr. Simpson’s clinical and research interests include advanced heart failure, interventional cardiology, complex electrophysiological procedures, high risk percutaneous coronary revascularization, cardiogenic shock, peripheral interventions, Asd/vsd Septal closure, and ARDS



See Publications

Texas Heart Institute Positions

  • Teaching Staff, Cardiovascular Disease Fellowship
  • Teaching Staff, Interventional Cardiology Fellowship
  • Teaching Staff, Advanced Heart Failure and Transplant Cardiology Fellowship


  • Cardiovascular disease
  • Advanced heart failure
  • Interventional Cardiology
  • Electrophysiology
  • Cardiac transplantation
  • Mechanical Circulatory Support
  • Peripheral Interventions


  • Undergraduate:

    All India Institute of Medical Sciences_

  • Medical School:

    All India Institute of Medical Sciences

  • Residency:

    Emory University

  • Fellowships:

    Baylor College of Medicine
    Texas Heart Institute

Academic & Clinical Affiliations

  • Baylor College of Medicine
  • Baylor St. Luke's Medical Center


  • Interventional Cardiology, American Board of Internal Medicine
  • Electrophysiology, American Board of Internal Medicine
  • Heart Failure and Cardiac Transplantation, American Board of Internal Medicine

Honors, Awards and Memberships

  • CCU Fellow of the Year at Texas Heart Institute (2006)
  • 98th percentile for Internal Medicine Boards (2005)
  • Member of 3 Person Jeopardy team from Emory for the American College of Physicians, Georgia Chapter Annual Meeting (2004 0
  • J. Willis Hurst Resident Achievement Award: Best Intern of the Year 2002-2003, Emory University Hospital (2003)
  • Outstanding performance during first year of residency by House staff evaluation committee (2003)
  • Best Intern of the Month July 2002, Emory University
  • Catherine Sorrel prize Best Postgraduate in Pediatrics (2000)
  • Merit Certificate National Neonatal Ventilation
  • Fellow of American College of Cardiology (2012)
  • Fellow of Heart Rhythm Society (2012)
  • Fellow of Society of Cardiovascular Angiography and Intervention (2012)
  • Texas Heart Institute Professional Staff