Amy R. Caivano

Amy grew up in Spring, TX and received a B.S. in Biology from Baylor University in Waco, TX. Since graduation she has worked in research labs at UT and Baylor and Encysive Pharmaceuticals. In 2008, after Pfizer purchased Encysive, Dr. James T. Willerson recruited her research group to join the department of Molecular Cardiology at THI where she remains today. Show full bio

Amy enjoys traveling to National Parks with her husband where they love to camp and hike. Baking delicious treats is a favorite pastime of her too.

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Texas Heart Institute Positions

Interests

  • Non-invasive diagnostic imaging technologies

Education

  • Undergraduate:

    Baylor University

Publications

Hickman, A., Koetsier, J., Kurtanich, T. et al. (2022). LFA-1 activation enriches tumor-specific T cells in a cold tumor model and synergizes with CTLA-4 blockade. J Clin Invest 132, e154152. https://doi.org/10.1172/JCI154152.
Bakthavatsalam, D., Craft, J. W., Kazansky, A. et al. (2020). Identification of Inhibitors of Integrin Cytoplasmic Domain Interactions With Syk. Front Immunol 11, 575085. https://doi.org/10.3389/fimmu.2020.575085.
Woodside, D. G., Tanifum, E. A., Ghaghada, K. B. et al. (2018). Magnetic resonance imaging of atherosclerotic plaque at clinically relevant field strengths (1T) by targeting the integrin α4β1. Sci Rep 8, 3733. https://doi.org/10.1038/s41598-018-21893-x.
Vanderslice, P., Biediger, R. J., Woodside, D. G. et al. (2013). Small molecule agonist of very late antigen-4 (VLA-4) integrin induces progenitor cell adhesion. J Biol Chem 288, 19414–19428. https://doi.org/10.1074/jbc.M113.479634.
Haidari, M., Zhang, W., Caivano, A. et al. (2012). Integrin α2β1 mediates tyrosine phosphorylation of vascular endothelial cadherin induced by invasive breast cancer cells. J Biol Chem 287, 32981–32992. https://doi.org/10.1074/jbc.M112.395905.
Gundlach, C. W., Caivano, A., Cabreira-Hansen, M. da G. et al. (2011). Synthesis and evaluation of an anti-MLC1 × anti-CD90 bispecific antibody for targeting and retaining bone-marrow-derived multipotent stromal cells in infarcted myocardium. Bioconjug Chem 22, 1706–1714. https://doi.org/10.1021/bc200309h.
Vanderslice, P., Woodside, D. G., Caivano, A. R. et al. (2010). Potent in vivo suppression of inflammation by selectively targeting the high affinity conformation of integrin α4β1. Biochem Biophys Res Commun 400, 619–624. https://doi.org/10.1016/j.bbrc.2010.08.114.

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