Texas Heart Institute Grand Rounds | John Elrod, PhD | Metabolic Control of Fibroblast Fate and Cardiac Fibrosis
The Denton A. Cooley Auditorium, B1 Level Cooley Bldg. (C060) 6770 Bertner Avenue, Houston, TX, United StatesJohn Elrod, PhD Director of the Cardiovascular Research Center in the Lewis Katz School of Medicine at Temple University Overview: We recently reported that glutaminolysis is essential for the epigenetic changes permissive to activation of the myofibroblast differentiation program and cardiac fibrosis. In fact, targeting these pathways is sufficient to reverse fibrosis in models of...