Cardiomyocyte Renewal Lab’s Discovery is Showcased in TMC News

Dr. James Martin, Director of Texas Heart Institute’s Cardiomyocyte Renewal Laboratory, was interviewed by TMC News regarding work he and other lab collaborators have conducted to take us one step closer to heart regeneration and renewal. The team’s research on genetic pathways revealed a direct correlation between the dystrophin glycoprotein complex (DGC) and the Hippo pathway, which inhibits cardiomyocyte proliferation, thereby restricting the heart’s ability to repair itself after injury.

“By manipulating a cell signaling channel called the Hippo pathway, Leach and Martin found they could trigger cardiomyocytes to multiply and essentially repair the scarred muscle, thus renewing the heart’s pumping function.” Read the full article here.