DCM II TRIAL (NCT04476901)
A Phase IIB randomized, placebo-controlled, multicenter study of the comparative efficacy and safety of transendocardial injection of allogeneic mesenchymal stem cells in patients with non-ischemic dilated cardiomyopathy NIDCM.
SPONSOR: University of Miami
ACTIVE ENROLLING SIGN UP
The Texas Heart Institute Center for Clinical Research is conducting a phase IIB, randomized, double-blinded, placebo-controlled trial that will evaluate the safety and effectiveness of transendocardial injection of human allogeneic mesenchymal stem cells (hMSCs) compared to placebo in patients with Non-Ischemic Dilated Cardiomyopathy (DCM). Patients will be followed at regular intervals over a one-year period to evaluate changes in cardiac function & quality of life.
- Males and females, between 18-80 years of age.
- Diagnosis of Non-Ischemic Dilated Cardiomyopathy
- Ejection Fraction of < 40%
- Willing to undergo DNA Test