Syed W. Ali
Texas Heart Institute Positions
- Sr. Programmer Analyst, Office of Research Administration
Publications
4862227
4THVEAYM
1
alternatives-to-animal-experimentation
10
date
desc
Ali
1805
https://www.texasheart.org/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22PMFEV4JW%22%2C%22library%22%3A%7B%22id%22%3A4862227%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Angelini%20et%20al.%22%2C%22parsedDate%22%3A%222018-08%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BAngelini%2C%20P.%2C%20Cheong%2C%20B.%20Y.%2C%20Lenge%20De%20Rosen%2C%20V.%20V.%20et%20al.%20%282018%29.%20High-risk%20cardiovascular%20conditions%20in%20sports-related%20sudden%20death%3A%20Prevalence%20in%205%2C169%20schoolchildren%20screened%20via%20cardiac%20magnetic%20resonance.%20%26lt%3Bi%26gt%3BTex%20Heart%20Inst%20J%26lt%3B%5C%2Fi%26gt%3B%20%26lt%3Bi%26gt%3B45%26lt%3B%5C%2Fi%26gt%3B%2C%20205%26%23x2013%3B213.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.14503%5C%2FTHIJ-18-6645%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.14503%5C%2FTHIJ-18-6645%26lt%3B%5C%2Fa%26gt%3B.%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22High-risk%20cardiovascular%20conditions%20in%20sports-related%20sudden%20death%3A%20Prevalence%20in%205%2C169%20schoolchildren%20screened%20via%20cardiac%20magnetic%20resonance%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paolo%22%2C%22lastName%22%3A%22Angelini%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benjamin%20Y.%22%2C%22lastName%22%3A%22Cheong%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Veronica%20V.%22%2C%22lastName%22%3A%22Lenge%20De%20Rosen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alberto%22%2C%22lastName%22%3A%22Lopez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carlo%22%2C%22lastName%22%3A%22Uribe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anthony%20H.%22%2C%22lastName%22%3A%22Masso%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Syed%20W.%22%2C%22lastName%22%3A%22Ali%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Barry%20R.%22%2C%22lastName%22%3A%22Davis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Raja%22%2C%22lastName%22%3A%22Muthupillai%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22James%20T.%22%2C%22lastName%22%3A%22Willerson%22%7D%5D%2C%22abstractNote%22%3A%22Improving%20preparticipation%20screening%20of%20candidates%20for%20sports%20necessitates%20establishing%20the%20prevalence%20of%20high-risk%20cardiovascular%20conditions%20%28hr-CVC%29%20that%20predispose%20young%20people%20to%20sudden%20cardiac%20death%20%28SCD%29.%20Our%20accurate%2C%20novel%20protocol%20chiefly%20involved%20the%20use%20of%20cardiac%20magnetic%20resonance%20%28CMR%29%20to%20estimate%20this%20prevalence.%20Middle%20and%20high%20school%20students%20from%20a%20general%20United%20States%20population%20were%20screened%20by%20means%20of%20questionnaires%2C%20resting%20electrocardiograms%2C%20and%20CMR%20to%20determine%20the%20prevalence%20of%203%20types%20of%20hr-CVC%3A%20electrocardiographic%20abnormalities%2C%20cardiomyopathies%2C%20and%20anomalous%20coronary%20artery%20origin%20from%20the%20opposite%20sinus%20with%20intramural%20coronary%20course%20%28ACAOS-IM%29.%20We%20examined%20the%20range%20of%20normal%20left%20ventricular%20size%20and%20function%20in%20the%20main%20study%20cohort%20%28schoolchildren%2011-14%20yr%20old%29.%20We%20defined%20diagnostic%20criteria%20for%20hr-CVC%20and%20compared%20the%20cardiac%20measurements%20of%20these%20younger%20participants%20with%20those%20of%20older%20children%20whom%20we%20examined%20%28age%2C%2015-18%20yr%29.%20From%205%2C169%20completed%20diagnostic%20studies%20%28mean%20participant%20age%2C%2013.06%20%5Cu00b1%201.78%20yr%29%2C%20CMR%20results%20revealed%2076%20previously%20undiagnosed%20cases%20of%20hr-CVC%20%281.47%25%20of%20the%20total%20cohort%29%3A%2011%20of%20dilated%20cardiomyopathy%20%2814.5%25%29%2C%203%20of%20nonobstructive%20hypertrophic%20cardiomyopathy%20%283.9%25%29%2C%2023%20ACAOS-IM%20cases%20%2830.3%25%3B%206%20left-ACAOS%20and%2017%20right-ACAOS%29%2C%204%20Wolff-Parkinson-White%20patterns%20%285.3%25%29%2C%2034%20prolonged%20QT%20intervals%20%2844.7%25%29%2C%20and%201%20Brugada%20pattern%20%281.3%25%29.%20Cardiomyopathies%20were%20significantly%20more%20prevalent%20in%20the%20older%20children.%20Of%20note%2C%20we%20identified%20959%20cases%20%2818.5%25%29%20of%20left%20ventricular%20noncompaction.%20If%20our%20estimate%20is%20accurate%2C%20only%201.47%25%20of%20school-age%20sports%20participants%20will%20need%20focused%20secondary%20evaluations%3B%20the%20rest%20can%20probably%20be%20reassured%20about%20their%20cardiac%20health%20after%20one%2030-minute%20screening%20study.%22%2C%22date%22%3A%22Aug%202018%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.14503%5C%2FTHIJ-18-6645%22%2C%22ISSN%22%3A%221526-6702%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22NNUFWYNJ%22%2C%22HVXNQK65%22%2C%22UJCYSTVM%22%2C%22CXMKC5YW%22%2C%22TCYVDH78%22%2C%22EA6QZY69%22%2C%22MXKXGRC3%22%2C%224THVEAYM%22%2C%228PULYTSK%22%5D%2C%22dateModified%22%3A%222021-03-31T21%3A15%3A11Z%22%7D%7D%2C%7B%22key%22%3A%22V8FEC87E%22%2C%22library%22%3A%7B%22id%22%3A4862227%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Angelini%20et%20al.%22%2C%22parsedDate%22%3A%222018-02-06%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BAngelini%2C%20P.%2C%20Cheong%2C%20B.%20Y.%2C%20Lenge%20De%20Rosen%2C%20V.%20V.%20et%20al.%20%282018%29.%20Magnetic%20resonance%20imaging-based%20screening%20study%20in%20a%20general%20population%20of%20adolescents.%20%26lt%3Bi%26gt%3BJ%20Am%20Coll%20Cardiol%26lt%3B%5C%2Fi%26gt%3B%20%26lt%3Bi%26gt%3B71%26lt%3B%5C%2Fi%26gt%3B%2C%20579%26%23x2013%3B580.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jacc.2017.11.051%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jacc.2017.11.051%26lt%3B%5C%2Fa%26gt%3B.%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Magnetic%20resonance%20imaging-based%20screening%20study%20in%20a%20general%20population%20of%20adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paolo%22%2C%22lastName%22%3A%22Angelini%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benjamin%20Y.%22%2C%22lastName%22%3A%22Cheong%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Veronica%20V.%22%2C%22lastName%22%3A%22Lenge%20De%20Rosen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20Alberto%22%2C%22lastName%22%3A%22Lopez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carlo%22%2C%22lastName%22%3A%22Uribe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anthony%20H.%22%2C%22lastName%22%3A%22Masso%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Syed%20W.%22%2C%22lastName%22%3A%22Ali%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Barry%20R.%22%2C%22lastName%22%3A%22Davis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Raja%22%2C%22lastName%22%3A%22Muthupillai%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22James%20T.%22%2C%22lastName%22%3A%22Willerson%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%22Feb%2006%2C%202018%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.jacc.2017.11.051%22%2C%22ISSN%22%3A%221558-3597%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22NNUFWYNJ%22%2C%22HVXNQK65%22%2C%22UJCYSTVM%22%2C%22CXMKC5YW%22%2C%22TCYVDH78%22%2C%22EA6QZY69%22%2C%22MXKXGRC3%22%2C%224THVEAYM%22%2C%228PULYTSK%22%5D%2C%22dateModified%22%3A%222018-05-07T15%3A22%3A04Z%22%7D%7D%2C%7B%22key%22%3A%22UXDLYEGQ%22%2C%22library%22%3A%7B%22id%22%3A4862227%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Hernandez%20et%20al.%22%2C%22parsedDate%22%3A%222015-10%22%2C%22numChildren%22%3A3%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BHernandez%2C%20R.%20E.%2C%20Singh%2C%20S.%20K.%2C%20Hoang%2C%20D.%20T.%20et%20al.%20%282015%29.%20Present-day%20hospital%20readmissions%20after%20left%20ventricular%20assist%20device%20implantation%3A%20a%20large%20single-center%20study.%20%26lt%3Bi%26gt%3BTex%20Heart%20Inst%20J%26lt%3B%5C%2Fi%26gt%3B%20%26lt%3Bi%26gt%3B42%26lt%3B%5C%2Fi%26gt%3B%2C%20419%26%23x2013%3B429.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.14503%5C%2FTHIJ-14-4971%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.14503%5C%2FTHIJ-14-4971%26lt%3B%5C%2Fa%26gt%3B.%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Present-day%20hospital%20readmissions%20after%20left%20ventricular%20assist%20device%20implantation%3A%20a%20large%20single-center%20study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ruben%20E.%22%2C%22lastName%22%3A%22Hernandez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Steve%20K.%22%2C%22lastName%22%3A%22Singh%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dale%20T.%22%2C%22lastName%22%3A%22Hoang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Syed%20W.%22%2C%22lastName%22%3A%22Ali%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22MacArthur%20A.%22%2C%22lastName%22%3A%22Elayda%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hari%20R.%22%2C%22lastName%22%3A%22Mallidi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22O.%20H.%22%2C%22lastName%22%3A%22Frazier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Deborah%20E.%22%2C%22lastName%22%3A%22Meyers%22%7D%5D%2C%22abstractNote%22%3A%22Left%20ventricular%20assist%20device%20%28LVAD%29%20therapy%20improves%20survival%2C%20hemodynamic%20status%2C%20and%20end-organ%20perfusion%20in%20patients%20with%20refractory%20advanced%20heart%20failure.%20Hospital%20readmission%20is%20an%20important%20measure%20of%20the%20intensity%20of%20LVAD%20support%20care.%20We%20analyzed%20readmissions%20of%20148%20patients%20%28mean%20age%2C%2053.6%20%5Cu00b1%2012.7%20yr%3B%2083%25%20male%29%20who%20received%20a%20HeartMate%20II%20LVAD%20from%20April%202008%20through%20June%202012.%20The%20patients%20had%20severe%20heart%20failure%3B%2060.1%25%20were%20in%20Interagency%20Registry%20for%20Mechanically%20Assisted%20Circulatory%20Support%20class%201%20or%202.%20All%20patients%20were%20observed%20for%20at%20least%2012%20months%2C%20and%20readmissions%20were%20classified%20as%20planned%20or%20unplanned.%20Descriptive%20and%20multivariate%20regression%20analyses%20were%20used%20to%20identify%20predictors%20of%20unplanned%20readmission.%20Twenty-seven%20patients%20%2818.2%25%29%20had%20no%20readmissions%20or%2069%20planned%20readmissions%2C%20and%20121%20patients%20%2881.8%25%29%20had%20460%20unplanned%20readmissions.%20The%20LVAD-related%20readmissions%20were%20for%20bleeding%2C%20thrombosis%2C%20and%20anticoagulation%20%28n%3D103%3B%2049.1%25%29%2C%20pump-related%20infections%20%28n%3D60%3B%2028.6%25%29%2C%20and%20neurologic%20events%20%28n%3D28%3B%2013.3%25%29.%20The%20readmission%20rate%20was%202.1%20per%20patient-year.%20Unplanned%20readmissions%20were%20for%20comorbidities%20and%20underlying%20cardiac%20disease%20%2854.3%25%29%20or%20LVAD-related%20causes%20%2845.7%25%29.%20In%20the%20unplanned-readmission%20rate%2C%20there%20was%20no%20significant%20difference%20between%20bridge-to-transplantation%20and%20destination-therapy%20patients.%20Unplanned%20readmissions%20were%20associated%20with%20diabetes%20mellitus%20%28odds%20ratio%20%5BOR%5D%3D3.3%3B%20P%3D0.04%29%20and%20with%20shorter%20mileage%20from%20residence%20to%20hospital%20%28OR%3D0.998%3B%20P%3D0.046%29.%20Unplanned%20admissions%20for%20LVAD-related%20sequelae%20and%20ongoing%20comorbidities%20were%20common.%20Diabetes%20mellitus%20and%20shorter%20distance%20from%20residence%20to%20hospital%20were%20significant%20predictors%20of%20readmission.%20We%20project%20that%20improved%20management%20of%20comorbidities%20and%20of%20anticoagulation%20therapy%20will%20reduce%20unplanned%20readmissions%20of%20LVAD%20patients%20in%20the%20future.%22%2C%22date%22%3A%22Oct%202015%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.14503%5C%2FTHIJ-14-4971%22%2C%22ISSN%22%3A%221526-6702%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22SE7HDD49%22%2C%22MU2Z9LKR%22%2C%224THVEAYM%22%5D%2C%22dateModified%22%3A%222018-05-07T15%3A22%3A36Z%22%7D%7D%5D%7D
Angelini, P., Cheong, B. Y., Lenge De Rosen, V. V. et al. (2018). High-risk cardiovascular conditions in sports-related sudden death: Prevalence in 5,169 schoolchildren screened via cardiac magnetic resonance. Tex Heart Inst J 45, 205–213. https://doi.org/10.14503/THIJ-18-6645.
Angelini, P., Cheong, B. Y., Lenge De Rosen, V. V. et al. (2018). Magnetic resonance imaging-based screening study in a general population of adolescents. J Am Coll Cardiol 71, 579–580. https://doi.org/10.1016/j.jacc.2017.11.051.
Hernandez, R. E., Singh, S. K., Hoang, D. T. et al. (2015). Present-day hospital readmissions after left ventricular assist device implantation: a large single-center study. Tex Heart Inst J 42, 419–429. https://doi.org/10.14503/THIJ-14-4971.
