Leading Research

A world class research facility.

2018 Research

The Texas Heart Institute is recognized internationally for research programs in cardiology, cardiovascular surgery, regenerative medicine and pathology. Our physicians and scientists conduct research ranging from gene therapy, stem cells and regenerative medicine, to wireless and battery-less pacemakers, ventricular assist devices (VADs) and artificial hearts.

Our Spirit and Drive for Discovery Continue

In the spring of 2018, Dr. Emerson Perin was appointed by the THI Board of Trustees to serve as the new Medical Director and is already making tremendous progress toward positioning THI for unparalleled growth.

Texas Heart Institute Opens Center for Clinical Research

Newly launched in early 2018, Texas Heart Institute’s (THI) Center for Clinical Research (CCR) supports all areas of cardiovascular clinical research, from protocol development to trial facilitation and post-trial assessment and reporting.

Leading Cell Therapy Research

The therapeutic potential of stem cells and cell therapy has captured the imagination of society and the medical community alike around the globe. The next discovery is not far, and 2018 was a productive year.

Research By The Numbers

> 500
Scientific Publications
Active Scientific and Clinical Research Projects
New Federal, State, Non-profit or Industry Contracts
Principal Investigators

Heart Health & Longevity For All Women

THI’s initiative to address women’s health issues was launched nearly 10 years ago with the support of community leaders. Led by Dr. Stephanie Coulter, the Women’s Center is addressing significant gaps in the care of women suffering from or at risk for developing heart and vascular disease.

Developing New Wireless, Shockless Pacemaker Technology

Texas Heart Institute (THI) doctors and engineers are committed to developing new pacing devices that will eliminate the need for batteries and wires and, more importantly, reduce the pain of the electrical shocks delivered by an implantable cardiac defibrillator.

A Treasured Texas Medical Center Resource Honors Dr. Cooley’s Passion for Innovation

One of the unique strengths of THI resides in the ability of its professional staff to perform surgical and interventional preclinical research. The preclinical research laboratory at THI reflects the high standard of excellence established by Dr. Cooley and Dr. Frazier over the last five decades.

Building the Future Today from Cells to Whole Hearts

Enthusiasm for the potential of regenerative medicine has resonated with patients and families around the world since the 1990s. Several local, state, and national partnerships have made possible new discoveries.

New Hope for Heart Repair After Heart Failure

THI researchers and their collaborators are conducting groundbreaking work that is taking us one step closer to heart regeneration and renewal.

Published in Scientific REPORTS (2018) Magnetic Resonance Imaging of Atherosclerotic Plaque at Clinically Relevant Field Strengths (1T) by Targeting the Integrin α4β1. Woodside DG, Tanifum EA, Ghaghada KB, Biediger RJ, Caivano AR, Starosolski ZA, Khounlo S, Bhayana S, Abbasi S, Craft JW Jr, Maxwell DS, Patel C, Stupin IV, Bakthavatsalam D, Market RV, Willerson JT, Dixon RAF, Vanderslice P, Annapragada AV. Sci Rep. 2018 Feb 27;8(1):3733.

The New Frontier of Molecular Cardiovascular Medicine

THI's molecular cardiology research benefits from an unparalleled leadership team with a strong track record of making significant discoveries in the use of small molecules for diagnostic and therapeutic medicine and shepherding these discoveries along the drug development track.