Todd R. Heallen, PhD

Texas Heart Institute Positions

Interests

  • Cardiac Regeneration

Education

  • Undergraduate:

    Texas A&M University

  • Postgraduate:

    UTHSCH-GSBS

  • Fellowships:

    Texas A&M IBT; Baylor College of Medicine

Academic & Clinical Affiliations

  • Baylor College of Medicine

Honors, Awards and Memberships

  • American Heart Association

Publications

Liu, S., Tang, L., Zhao, X. et al. (2021). Yap promotes noncanonical Wnt signals from cardiomyocytes for heart regeneration. Circ Res 129, 782–797. https://doi.org/10.1161/CIRCRESAHA.121.318966.
Liu, S., Li, K., Wagner Florencio, L. et al. (2021). Gene therapy knockdown of Hippo signaling induces cardiomyocyte renewal in pigs after myocardial infarction. Sci Transl Med 13, eabd6892. https://doi.org/10.1126/scitranslmed.abd6892.
Heallen, T. R., Kadow, Z. A., Wang, J. et al. (2020). Determinants of cardiac growth and size. Cold Spring Harb Perspect Biol 12. https://doi.org/10.1101/cshperspect.a037150.
Heallen, T. R., Kadow, Z. A., Kim, J. H. et al. (2019). Stimulating cardiogenesis as a treatment for heart failure. Circ Res 124, 1647–1657. https://doi.org/10.1161/CIRCRESAHA.118.313573.
Monroe, T. O., Hill, M. C., Morikawa, Y. et al. (2019). YAP partially reprograms chromatin accessibility to directly induce adult cardiogenesis in vivo. Dev Cell 48, 765-779.e7. https://doi.org/10.1016/j.devcel.2019.01.017.
Wang, J., Liu, S., Heallen, T. et al. (2018). The Hippo pathway in the heart: pivotal roles in development, disease, and regeneration. Nat Rev Cardiol 15, 672–684. https://doi.org/10.1038/s41569-018-0063-3.
Heallen, T. R. and Martin, J. F. (2018). Heart repair via cardiomyocyte-secreted vesicles. Nat Biomed Eng 2, 271–272. https://doi.org/10.1038/s41551-018-0239-5.
Leach, J. P., Heallen, T., Zhang, M. et al. (2017). Hippo pathway deficiency reverses systolic heart failure after infarction. Nature 550, 260–264. https://doi.org/10.1038/nature24045.
Morikawa, Y., Heallen, T., Leach, J. et al. (2017). Dystrophin-glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation. Nature 547, 227–231. https://doi.org/10.1038/nature22979.
Tao, G., Kahr, P. C., Morikawa, Y. et al. (2016). Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury. Nature 534, 119–123. https://doi.org/10.1038/nature17959.

Recent News

Girl Scouts Project Heart 2024 STEM Innovation Day with The Texas Heart Institute…and Cool-E

The Texas Heart Institute to Host Brownie & Junior Girl Scouts to Earn Project Heart Smart Patch The Texas Heart...

Alternative Metrics Reveal THI’s Most Popular Scientific Articles from 2021

The impact of a scientific article is often described in terms of how many times the article has been cited...

New Texas Heart Institute Study Outlines Additional Reasons for Optimism Related to Heart Regeneration

The New Paper Follows Closely on the Heels of a Related Publication on Cardiomyocyte Renewal Following a Heart Attack  ...