Saleem Raslan, MD

Publications

4862227 IWWMKGLS 1 alternatives-to-animal-experimentation 10 date desc Raslan 38857 https://www.texasheart.org/wp-content/plugins/zotpress/
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Alkhouli, M., Chaker, Z., Alqahtani, F. et al. (2020). Outcomes of routine intracardiac echocardiography to guide left atrial appendage occlusion. JACC Clin Electrophysiol 6, 393–400. https://doi.org/10.1016/j.jacep.2019.11.014.
Alkhouli, M., Raslan, S., Zeb, I. et al. (2019). Percutaneous closure of intra-MitraClip leak: Impact of occluder device type on closure success and hemolysis. JACC Cardiovasc Interv 12, e201–e203. https://doi.org/10.1016/j.jcin.2019.05.046.
Iqbal, F., Durham, W. J., Melhem, A. et al. (2018). Sex-dependent difference in the relationship between adipose-tissue cholesterol efflux and estradiol concentrations in young healthy humans. Int J Dev Neurosci 64, 59–62. https://doi.org/10.1016/j.ijdevneu.2017.07.001.
Iqbal, F. M., Hage, F. G., Ahmed, A. et al. (2012). Comparison of the prognostic value of normal regadenoson with normal adenosine myocardial perfusion imaging with propensity score matching. JACC Cardiovasc Imaging 5, 1014–1021. https://doi.org/10.1016/j.jcmg.2012.04.009.
Hage, F. G., Raslan, S., Dean, P. et al. (2012). Real time three-dimensional transthoracic echocardiography in congenital heart disease. Echocardiography 29, 220–231. https://doi.org/10.1111/j.1540-8175.2011.01555.x.
Hage, F. G., Dean, P., Raslan, S. et al. (2012). Real time three-dimensional echocardiography for the evaluation of cardiomyopathy. Echocardiography 29, 76–87. https://doi.org/10.1111/j.1540-8175.2011.01566.x.
Raslan, S., Nanda, N. C., Lloyd, L. et al. (2011). Incremental value of live/real time three-dimensional transesophageal echocardiography over the two-dimensional technique in the assessment of sinus of valsalva aneurysm rupture. Echocardiography 28, 918–920. https://doi.org/10.1111/j.1540-8175.2011.01461.x.
Lloyd, L., Raslan, S., Nanda, N. C. et al. (2011). Transesophageal echocardiographic detection of thrombus superimposed on metastatic left atrial tumor. Echocardiography 28, 591–592. https://doi.org/10.1111/j.1540-8175.2011.01426.x.