Chu-Huang (Mendel) Chen, MD, PhD

Texas Heart Institute Positions

  • Director, Vascular and Medicinal Research, Molecular Cardiology Research

Education

  • Postgraduate:

    Texas Tech University

  • Medical School:

    Kaohsiung Medical University, Taiwan

  • Residency:

    Chang-Gung Memorial Hospital, Taiwan (Pathology)
    Maryland General Hospital & Univ. of Maryland (Internal Medicine)

  • Fellowships:

    Baylor College of Medicine

Academic & Clinical Affiliations

Honors, Awards and Memberships

  • The Texas Heart Institute Academic Professional Staff
  • Mentored Outstanding Scholars (Ministry of Science and Technology-Taiwan)2017-2020
  • Editorial board, Kaohsiung Journal of Medical Sciences, 2016–present
  • Outstanding Faculty Teaching Award of China Medical University, 2015
  • Best Clinical Teacher Award of China Medical University Hospital, 2015
  • Outstanding Alumni Award, Kaohsiung Medical University, Taiwan, 2014--life time
  • 12th Generation Chen Style Tai Chi Selected Disciple, 2013–life time
  • Editorial board, Biomedical Journal 2013–present
  • Elite physician of Internal Medicine in China Medical University Hospital, 2013
  • Philip Morris Research Award, 2005–2008
  • Texas Medical Center/NASA Cooperative Research Grant, 1995–1996
  • American Diabetes Association
  • AHA, Atherosclerosis Council
  • International Atherosclerosis Society
  • American Association for the Advancement of Science
  • The Angiogenesis Society

Publications

Kraler, S., Wenzl, F. A., Vykoukal, J. et al. (2023). Low-density lipoprotein electronegativity and risk of death after acute coronary syndromes: A case-cohort analysis. Atherosclerosis 376, 43–52. https://doi.org/10.1016/j.atherosclerosis.2023.05.014.
Chen, T.-C., Hsu, W.-L., Wu, C.-Y. et al. (2023). Effect of omega-6 linoleic acid on neurobehavioral development in Caenorhabditis elegans. Prostaglandins Leukot Essent Fatty Acids 191, 102557. https://doi.org/10.1016/j.plefa.2023.102557.
Wu, C.-H., Hsu, W.-L., Tsai, C.-C. et al. (2023). 7,10,13,16-Docosatetraenoic acid impairs neurobehavioral development by increasing reactive oxidative species production in Caenorhabditis elegans. Life Sci 319, 121500. https://doi.org/10.1016/j.lfs.2023.121500.
Hosomi, K., Kawashima, H., Nakano, A. et al. (2022). NanoSPECT imaging reveals the uptake of 123I-labeled oxidized low-density lipoprotein in the brown adipose tissue of mice via CD36. Cardiovasc Res, cvac167. https://doi.org/10.1093/cvr/cvac167.
Chang, C.-K., Chang, K.-H., Cheng, W.-C. et al. (2022). Lipid metabolomic signature might predict subclinical atherosclerosis in patients with active rheumatoid arthritis. Clin Exp Rheumatol. https://doi.org/10.55563/clinexprheumatol/int08c.
Lee, H.-C., Akhmedov, A. and Chen, C.-H. (2022). Spotlight on very-low-density lipoprotein as a driver of cardiometabolic disorders: Implications for disease progression and mechanistic insights. Front Cardiovasc Med 9, 993633. https://doi.org/10.3389/fcvm.2022.993633.
Lin, K.-C., Ting, L.-L., Chang, C.-L. et al. (2021). Ex vivo expanded circulating tumor cells for clinical anti-cancer drug prediction in patients with head and neck cancer. Cancers (Basel) 13, 6076. https://doi.org/10.3390/cancers13236076.
Tsai, M.-H., Chao, H.-R., Hsu, W.-L. et al. (2021). Analysis of polybrominated diphenyl ethers and lipid composition in human breast milk and their correlation with infant neurodevelopment. Int J Environ Res Public Health 18, 11501. https://doi.org/10.3390/ijerph182111501.
Chang, C.-K., Cheng, W.-C., Ma, W.-L. et al. (2021). The potential role of electronegative high-density lipoprotein H5 subfraction in RA-related atherosclerosis. Int J Mol Sci 22, 11419. https://doi.org/10.3390/ijms222111419.
Chang, C.-K., Chen, P.-K., Chen, C.-C. et al. (2021). Increased levels of omega-3 fatty acids and DHA are linked to pain reduction in rheumatoid arthritis patients treated with Janus kinase inhibitors. Nutrients 13, 3050. https://doi.org/10.3390/nu13093050.