Darren G. Woodside, PhD

Darren Woodside, Ph.D., is the Vice President for Research and Director of the Flow Cytometry and Imaging Core at the Texas Heart Institute. Show full bio

Dr. Woodside’s research centers around the role that cell adhesion plays in cardiovascular and autoimmune diseases, and the development of novel means to identify and treat these diseases. Prior to assuming the position of Vice President, he served as Associate Director of the Molecular Cardiology Research Laboratories at THI and Associate Director of Drug Discovery at Encysive Pharmaceuticals. He was awarded his Ph.D. from the University of Texas MD Anderson Cancer Center’s Department of Immunology and was a post-doctoral fellow at The Scripps Research Institute.

He has authored numerous publications, served on Editorial Review Boards, and currently chairs the NIH Innovative Immunology Study Section.

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Texas Heart Institute Positions

Vice President for Research, Administration
Director, Flow Cytometry and Imaging, Molecular Cardiology Research

Interests

Inflammation
Non-invasive diagnostic imaging technologies

Education

Undergraduate:

Queen's University at Kingston
Postgraduate:

University of Texas MD Anderson Cancer Center, Graduate School of Biomedical Sciences
Fellowships:

The Scripps Research Institute

Honors, Awards and Memberships

Publications

Pogostin, B. H., Yu, M. H., Azares, A. R. et al. (2022). Multidomain peptide hydrogel adjuvants elicit strong bias towards humoral immunity. Biomater Sci. https://doi.org/10.1039/d2bm01242a.

Hickman, A., Koetsier, J., Kurtanich, T. et al. (2022). LFA-1 activation enriches tumor-specific T cells in a cold tumor model and synergizes with CTLA-4 blockade. J Clin Invest 132, e154152. https://doi.org/10.1172/JCI154152.

Lokugamage, N., Chowdhury, I. H., Biediger, R. J. et al. (2021). Use of a small molecule integrin activator as a systemically administered vaccine adjuvant in controlling Chagas disease. NPJ Vaccines 6, 114. https://doi.org/10.1038/s41541-021-00378-5.

Lopez-Silva, T. L., Leach, D. G., Azares, A. et al. (2020). Chemical functionality of multidomain peptide hydrogels governs early host immune response. Biomaterials 231, 119667. https://doi.org/10.1016/j.biomaterials.2019.119667.

Bakthavatsalam, D., Craft, J. W., Kazansky, A. et al. (2020). Identification of Inhibitors of Integrin Cytoplasmic Domain Interactions With Syk. Front Immunol 11, 575085. https://doi.org/10.3389/fimmu.2020.575085.

Woodside, D. G. (2019). Nanoparticle imaging of vascular inflammation and remodeling in atherosclerotic disease. Current Cardiovascular Imaging Reports 12. https://doi.org/10.1007/s12410-019-9501-9.

Woodside, D. G., Tanifum, E. A., Ghaghada, K. B. et al. (2018). Magnetic resonance imaging of atherosclerotic plaque at clinically relevant field strengths (1T) by targeting the integrin α4β1. Sci Rep 8, 3733. https://doi.org/10.1038/s41598-018-21893-x.

Kumar, V. A., Liu, Q., Wickremasinghe, N. C. et al. (2016). Treatment of hind limb ischemia using angiogenic peptide nanofibers. Biomaterials 98, 113–119. https://doi.org/10.1016/j.biomaterials.2016.04.032.

Deng, Y., Yang, Z., Terry, T. et al. (2016). Prostacyclin-producing human mesenchymal cells target H19 lncRNA to augment endogenous progenitor function in hindlimb ischaemia. Nat Commun 7, 11276. https://doi.org/10.1038/ncomms11276.

Bakthavatsalam, D., Soung, R. H., Tweardy, D. J. et al. (2014). Chaperonin-containing TCP-1 complex directly binds to the cytoplasmic domain of the LOX-1 receptor. FEBS Lett 588, 2133–2140. https://doi.org/10.1016/j.febslet.2014.04.049.

Texas Heart Institute Positions

Interests

Education

Undergraduate:

Postgraduate:

Fellowships:

Honors, Awards and Memberships

Publications

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