Peripheral Artery Disease (PAD) occurs when arteries in the arms and legs (most often the legs) become narrowed by plaque. The plaque causes decreased blood flow to the leg muscles resulting in pain in one or both of your legs when you exercise (such as during walking). This pain is referred to as Intermittent Claudication. Patients with PAD are also at increased risk for heart attacks and strokes.
The Texas Heart Institute Stem Cell Center in Houston, Texas is actively screening eligible patients for a clinical study for patients who have been diagnosed with PAD. This study is called PACE (Patients with Intermittent Claudication injected with ALDH Bright Cells).
This study will investigate the safety and effect of injecting bone marrow derived stem cells directly into the leg muscle of patients with PAD to help improve blood flow to the muscle and possibly increase the amount of time patients can walk before experiencing leg pain.
Many factors are considered before enrolling patients into a research study. Please contact the Stem Cell Center study staff for any questions.
If you are a patient and wish to be considered for enrollment in a trial, please call us toll free at 1-866-924-STEM (7836) or complete our secure online Patient Information Form.
If you are a physician and would like to refer a patient for consideration, please contact a study coordinator at 832-355-9405.