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How is left ventricular diastolic dysfunction (LVDD) treated? 

I have been recently diagnosed with trivial/mild mitral valve regurgitation (due to annular calcification) and left ventricular diastolic dysfunction (stage 1). I am currently taking Crestor 20 mg, Coversyl 2 mg, and Aspirin 325 mg. I have impaired glucose and taking 500 mg Metformin twice a day. I would greatly appreciate if you could advise me on how LVDD is aggressively treated.  Can the LVDD be reversed?  Any additional info would be appreciated.  Thanks very much in advance. 

submitted by William from Toronto, Ontario, Canada on 7/23/2013


by Texas Heart Institute cardiologist, Patrick J. Cook, MD  

Patrick J. Cook, MD I'm not sure what Coversyl is. Diastolic dysfunction, or as it is more commonly called "heart failure with preserved ejection fraction", is difficult to treat. There are certain echo parameters that are often seen with it. It can be seen with CAD [coronary artery disease] or with HTN [hypertension]. It  is commonly seen in elderly women. It is important to make sure the patient stays in sinus rhythm if possible, or, if they can't be kept out of afib [atrial fibrillation], at least control the rate. ACE inhibitors or ARBs are often given, but there is little evidence of efficacy. If fluid overload is a problem, diuretics are used, but BP can plummet if a patient is over-diuresed. If there is no "reversible cause" like CAD, therapeutic options are limited. .

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Updated July 2013
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