Course Overview
This presentation is devoted to a discussion of pathogenetic mechanisms of atrial fibrillation including triggers, substrate, autonomic and genetic factors. Dr. Scheinman also discusses the possible therapeutic implications of the findings.

Educational Objectives
The intended result of this activity is increased knowledge. At the conclusion of this program, participants will be able to

• List the known atrial areas that may serve as triggers for atrial fibrillation.
• List possible abnormal substrates and their relationship to scroll wave activity and anchor points.
• List how specific pathogenetic mechanisms affect current treatment modalities.

Target Audience
Individuals who will benefit by participating in this CME enduring material include cardiologists, physicians, electrophysiologists, and others involved in diagnosing and treating atrial fibrillation.

Evaluation / Feedback
We value your comments; please send your suggestions and comments to the office of continuing medical education at Texas Heart Institute.

Accreditation Statement
Texas Heart Institute is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

Texas Heart Institute designates this educational activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should only claim credit commensurate with the extent of their participation in the activity.

The estimated time to complete this activity, including review of the materials is 1 hour.

Term of Approval  
March 2007 through March 2010. Original release date: March 30, 2007.

Peer Review
In March 2007, this continuing medical education activity was reviewed by James J. Ferguson III, MD, FACC—Associate Director, Clinical Cardiology Research, THI; Co-Chairman, Medical Education Committee, THI; Chairman, Research Committee, THI. Houston, TX.

Disclosure of Relationships
It is the intent of the Texas Heart Institute to ensure that its educational mission and its continuing medical activities in particular, should not be influenced by the special interests of individuals associated with its program.

Faculty Disclosure
In accordance with the guidelines of the Accreditation Council for Continuing Medical Education, these faculty members have disclosed the following relationships, either with one or more of the manufacturers of commercial products discussed, or with one or more of the corporate organizations offering educational grants for this continuing medical education activity.

Mel Scheinman, MD has the following disclosures, relevant to this program: 

• Speakers’ Bureau—Guidant.

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