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News Release 2006 - February 27

Dr. Bud Frazier and His Team Perform 1,000th Heart Transplant at the Texas Heart Institute at St. Luke's Episcopal Hospital

HOUSTON (February 27, 2006)  Cardiovascular surgeon Bud Frazier, M.D., and his team have completed their 1,000th heart transplant at the Texas Heart Institute at St. Luke’s Episcopal Hospital. It is believed Dr. Frazier has performed more heart transplants than any other surgeon in the world. Dr. Frazier is chief of Cardiopulmonary Transplantation and director of Surgical Research at the Texas Heart Institute (THI) at St. Luke’s. Dr. Denton A. Cooley, president and surgeon-in-chief of THI at St. Luke’s, performed the first successful heart transplant in the U.S. at St. Luke’s in 1968.

“The current program began with the advent of cyclosporine (in 1982), which allowed our patients more protection against systemic infections while being immunosuppressed,” said Dr. Frazier. “I have always felt the limitation of heart transplantation is that it is only possible because of the misfortune of others. The families who make the choice to donate the organs of their loved ones are truly courageous.”

The patient who received the 1000th heart transplant is no stranger to milestones. Everardo Flores, now 21, first came to the Texas Heart Institute at St. Luke’s in 2003 suffering from cardiomyopathy of an unknown cause and heart failure. He was the first patient in the U.S. to receive the HeartMate II heart assist device which supported him for more than two years before an infection required explantation of the device in November. During the last two years, Mr. Flores has traveled to medical conferences across the country to share his experience with the heart assist device.

“I felt lucky to have the HeartMate II because it allowed me to live a fairly normal life. I could play with my daughter where before, I was too sick to even pick her up. I was able to go on with my life, help my dad at his shop and explore career choices. And it was interesting to meet all those medical people and help them learn about the device,” said Mr. Flores. “I’m grateful the device helped me live this long, and now I’m thrilled to have a new heart.”

“The HeartMate II served its purpose as a bridge to transplant. Even though we had to take it out, we found his heart had recovered some function and we were able to manage his heart failure symptoms in the hospital until a donor heart could be found. It’s very gratifying to be able to help someone so young have a new chance at life,” said Dr. Frazier.

Although Dr. Frazier and his team have unrivaled experience with heart transplantation, they are still refining their understanding of the lifesaving treatment. For example, they have been studying new drugs to prevent organ rejection and the effects of a drug treatment for anemia in heart transplant recipients. For the last 40 years, Dr. Frazier has devoted much of his research to the development of new devices to allow for heart recovery as well as being effective bridges to transplantation.

World-renowned cardiovascular surgeon Denton A. Cooley, MD, founded the Texas Heart Institute in 1962 for the study and treatment of diseases of the heart and blood vessels. The Texas Heart Institute is dedicated to reducing the devastating toll of cardiovascular disease through innovative programs in research, education and improved patient care.Together with the Institute's clinical partner, St. Luke's Episcopal Hospital, for the past 15 years it has been ranked among the nation's top ten heart centers in an annual survey published by U.S. News & World Report. For more information about the Institute, please visit www.texasheart.org.

St. Luke’s Episcopal Health System comprises the flagship St. Luke’s Episcopal Hospital in the Texas Medical Center, founded in 1954 by the Episcopal Diocese of Texas; St. Luke’s Community Medical Center–The Woodlands, opened in 2003; St. Luke’s Episcopal Health Charities, a charity devoted to assessing and enhancing community health, especially among the underserved; and Kelsey-Seybold Management, LLP, overseeing 21 area clinic locations. St. Luke’s Episcopal Hospital is home to the Texas Heart Institute, founded in 1962 by Denton A. Cooley, MD, and consistently ranked among the top 10 cardiology and heart surgery centers in the nation by U.S. News & World Report. Affiliated with several nursing schools and two medical schools, St. Luke’s serves as the primary adult teaching hospital for Baylor College of Medicine. St. Luke’s was the first hospital in Texas named a Magnet hospital for nursing excellence, and the Health System has been recognized by FORTUNE as among “100 Best Companies to Work For” (2002, 2004 and 2005) and by Houston Business Journal as a top employer in Houston for three consecutive years.

Contacts:

Kathy Watson
Texas Heart Institute
832-355-6569
kwatson@heart.thi.tmc.edu

Melinda Muse
St. Luke's Episcopal Hospital
832-355-3040
mmuse@sleh.com

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